I-MAB Biopharma and AGC Biologics Partner on Late-Phase Project

Global CDMO utilizes Seattle facility’s mammalian biologics expertise to support late-stage clinical trials for leading international biopharma organization

Seattle, Dec. 13, 2021 (GLOBE NEWSWIRE) — AGC Biologics, a leading global Biopharmaceutical Contract Development and Manufacturing Organization (CDMO), today announced a new partnership with I-MAB Biopharma (Nasdaq: IMAB). The I-MAB treatment being developed is approaching late-phase clinical trials and AGC Biologics will manufacture the materials at its site in Seattle, while also supporting the launch readiness of I-MAB’s product.

AGC Biologics operates multiple mammalian cGMP manufacturing lines and a variety of scales at its Seattle cell culture facility. The site is designed for capacity and technological flexibility, and has an extensive variety of single-use and stainless steel systems that meet the latest guidelines required for cGMP compliance. The Seattle site also has a long history of successful inspections by the FDA and the site is approved for commercial production. All of these features and capabilities combined make the AGC Biologics Seattle facility an ideal location to support I-MAB’s goals and bring this treatment through its next clinical phase.

“We look forward to partnering with a true pioneer in innovative clinical research and development, and working together to help bring I-MAB’s product through the final clinical stages and to commercialization,” said Jean-Baptiste Agnus, Chief Business Officer of AGC Biologics. “Our team in Seattle is an ideal customer-focused group of scientists to help I-MAB in its promising journey for this treatment.”

AGC Biologics’ Seattle facility has capabilities for developing a wide range of mammalian and microbial programs, and has delivered several approved commercial products.

To learn more about the biologics capabilities AGC Biologics offers across its network of seven global facilities visit www.agcbio.com/capabilities.

About AGC Biologics
AGC Biologics is a leading global biopharmaceutical Contract Development and Manufacturing Organization (CDMO) with a strong commitment to delivering the highest standard of service as we work side-by-side with our clients and partners, every step of the way. We provide world-class development and manufacture of mammalian and microbial-based therapeutic proteins, plasmid DNA (pDNA), viral vectors, and genetically engineered cells. Our global network spans the U.S., Europe, and Asia, with cGMP-compliant facilities in Seattle, Washington; Boulder and Longmont, Colorado; Copenhagen, Denmark; Heidelberg, Germany; Milan, Italy; and Chiba, Japan and we currently employ more than 2,000 employees worldwide. Our commitment to continuous innovation fosters the technical creativity to solve our clients’ most complex challenges, including specialization in fast-track projects and rare diseases. AGC Biologics is the partner of choice. To learn more, visit www.agcbio.com.

Nick McDonald
AGC Biologics
(425) 419-3555
nmcdonald@agc.com

Sequence by Chain Looks to Capture the Permissioned Blockchain Market

Featured Image for Chain

Featured Image for Chain

CHARLESTOWN, Saint Kitts and Nevis, Dec. 13, 2021 (GLOBE NEWSWIRE) — Chain, a ledger-as-a-service blockchain launched in 2014, is ready to bring its flagship product, Sequence, to the hands of institutional and business clients. Chain was a prominent blockchain start-up that received funding from, and partnered with major financial institutions, such as Visa, Citibank, and others, to launch custom blockchain products. Chain was acquired by Stellar back in 2018 for what was at the time one of the largest M&A deals in the entire blockchain space, at reportedly $500M.

Since then, Chain has been reacquired to continue developing its ledger-as-a-service product, Sequence. There is also an open source version aptly named Chain Core, available for developers.

The code base is undergoing a major overhaul by the new team with an expectation to launch Sequence v2 and Chain Core v2 in 2022.

“We are absolutely committed to bringing blockchain technology to major financial players in the legacy banking space. The original Chain team built novel software that was piloted by many until they ultimately merged with Stellar to create Interstellar, running on a public blockchain. However, legacy clients want close-ended systems, ones they can control. If we bring the efficiency of a blockchain and give them the close-ended tools they require, the space can be widely disrupted by Chain’s products. We are keen to bringing this to fruition,” said Deepak Thapliyal, Chain’s Chief Executive Officer.

Chain has also launched its native Chain Token, a self-described Ethereum based token that grants users access to discounts on Sequence as well as access to premium services on the product line. Chain Tokens will eventually enable governance and control over its DAO and public network.

Chain is positioned within a very niche area where there is low competition. Most highly used blockchains are public networks that require smart contracts to operate in a centralized manner in order to build out close-ended systems. These public blockchains can result in outages, delayed processing, and/or hard forks which can disrupt how legacy institutions conduct business. This is where Chain’s products can be leveraged to benefit from blockchain technology within their own environments.

To further promote its branding and products, Chain has teamed up with Twitter to launch a custom branded Chain Emoji featuring 5 hashtags: #ChainProtocol #SequenceLedger #CHNToken #ChainCore & #ChainTxVM. Chain aims to bring its market-ready products to the hands of clients looking for more control through higher efficiency of a blockchain.

About Chain

Chain is cloud blockchain protocol that enables organizations to build better financial services from the ground up powered by Sequence, a ledger-as-service product that can be deployed within minutes through the Sequence Portal, and Chain Core, a permissioned open-source blockchain for developers. Learn more at chain.com

Press Inquiries

For all press, analyst, and speaking opportunities contact press@chain.com

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Tai Ji Men Observes International Anti-Corruption Day and Human Rights Day

The global community calls on the Taiwanese government to rectify the Tai Ji Men case and protect religious freedom and human rights

Protest in Washington, D.C.

Representatives of Tai Ji Men dizi (disciples) protest against the violations of their religious freedom and human rights by the Taiwanese government in Washington, D.C. on December 5, 2021.

WASHINGTON, Dec. 13, 2021 (GLOBE NEWSWIRE) — Nearly 60 representatives of worldwide Tai Ji Men dizi (disciples) gathered in Washington, D.C., on December 5-7 to protest against the Taiwanese government’s indifference to their case, a major case of religious persecution, and against its connivance with a few bureaucrats who have broken the law and abused their power. Over the past 25 years, Tai Ji Men has been persecuted through both judicial and tax measures, and its sacred land intended for a spiritual center was illegally and forcibly auctioned last year. Tai Ji Men’s shifu (master) and dizi have exhausted all remedies available to them in Taiwan, but to no avail! Concerned that their families in Taiwan might be purged, Tai Ji Men dizi in the United States presented their case to several Taipei Economic and Cultural Offices around the world, but only received deceptive responses from the Ministry of Justice, Ministry of Finance, National Taxation Bureau, and others. They had no choice but to hold the first international press conference since its inception 55 years ago, in Washington, D.C., the world’s political capital, to seek international support, reveal the truth about the bogus Tai Ji Men case, and call on the Taiwanese government to implement transitional justice.

On December 5, dozens of representatives of Tai Ji Men dizi, ranging in age from 10 to 80 years old, protested in front of the Thomas Jefferson Memorial, Lincoln Memorial, Washington Monument, the White House, and National Christmas Tree, hoping that by courageously stepping forward and revealing the truth, more people will understand this fabricated and unjust Tai Ji Men case, and they demanded the Taiwanese government to administer policies in accordance with the law, return Tai Ji Men’s sacred land, which was forcibly confiscated, and protect people’s religious freedom and human rights! Many other visitors expressed support for Tai Ji Men’s worthy cause, and some even joined the protest, holding signs in support of universal human rights and religious freedom.

On the morning of December 6, the Center for Studies on New Religions (CESNUR) and Human Rights Without Frontiers co-organized an international forum, under the theme of “Human Rights and Anti-Corruption: The Tai Ji Men Case” in honor of International Anti-Corruption Day (December 9) and Human Rights Day (December 10). Several international scholars and experts, who are concerned about the Tai Ji Men case, as well as Tai Ji Men dizi, participated in the conference in person or virtually, with many more attending via Zoom and YouTube.

Prof. Massimo Introvigne, an Italian sociologist who is the founder and managing director of CESNUR, and the editor-in-chief of Bitter Winter, stated, “In the Tai Ji Men case, bureaucrats forgot, or willingly ignored, that they are ‘civil servants’ and should work at the service of the deeper aims of the state, human rights and the well-being of citizens. Instead, they believed they were called to protect bureaucracy for bureaucracy’s sake, not to mention they tried to enrich themselves through the bonuses.”

PierLuigi Zoccatelli, professor of Sociology of Religions at Pontifical Salesian University, Italy, criticized Taiwan’s bonus system, saying, “Unless the bureaucrats are all angels, the system also becomes a machine to generate corruption.” Prof. Zoccatelli remarked that corruption played a crucial role in the Tai Ji Men case, resulting in violations of Tai Ji Men’s human rights, and that because Taiwan made the International Covenant on Economic, Social and Cultural Rights (ICESCR) part of its domestic law, it should enforce the Covenant and correct the injustices against Tai Ji Men.

Willy Fautré, co-founder and director of Human Rights Without Frontiers, pointed out, “It is obvious that in Taiwan there are abuses by the administrative power for private gain. What is at stake here is the system of bonuses which viciously leads to the over-collection of taxes and even the fabrication of tax evasion taxes. This is an abuse of power for private financial gain.”

Camelia Marin, deputy director of the NGO Soteria International (Denmark), conveyed her admiration for Tai Ji Men’s efforts to insist on doing what is right: “Let me express my gratitude for the perseverance and optimism that Tai Ji Men shows and shares by standing for their case, for their rights, bringing hope to the many others around the world who have not yet found justice but are still persecuted.” She urged the Taiwanese government to rectify the Tai Ji Men case: “Now is the time to solve it.”

Alessandro Amicarelli, a London-based human rights lawyer and the president of the European Federation for Freedom of Belief (FOB), said, “Corruption is at the very core of the Tai Ji Men case.” He believes that it is now time to move from prosecuting the innocent to prosecuting the rogue bureaucrats, who have wrongly prosecuted Tai Ji Men and violated their human rights.

Eight Tai Ji Men dizi spoke out against the persecution of themselves and their families by Taiwanese authorities, calling on the Taiwanese government to rectify the mistakes made by the unscrupulous government officials and return to Tai Ji Men the justice it deserves.

On the afternoon of December 6, Tai Ji Men dizi visited the Taipei Economic and Cultural Representative Office in the U.S. again. It was their fourth visit to this Office. They hoped to meet with Representative Hsiao, who could help pass on their concern and message about the Tai Ji Men case to the Taiwanese government to immediately resolve the issue. They protested for over two and a half hours, but no one from the office came out to respond to their demands.

On December 7, the first international press conference on the Tai Ji Men case was held in the world’s political capital, and the news was published on Yahoo, the Toronto Sun, and other media outlets. Prof. Massimo Introvigne, an Italian sociologist and the editor-in-chief of Bitter Winter, introduced the event and explained that Bitter Winter is known for its support for Taiwan, and that the Tai Ji Men dizi (disciples) in the United States also love their country of origin. It is precisely because of their love for Taiwan that they want it to eliminate the ghosts of its authoritarian past and improve its international image as a truly democratic country where human rights prevail.

Prof. Introvigne had studied the Tai Ji Men case for years and emphasized, “The Taiwan government is not understanding the Tai Ji Men case in its proper terms. It’s not a domestic or technical tax case, but it’s a human rights case based on freedom of religion or belief.” “It’s a case impacting negatively on the international image of Taiwan,” said Prof. Introvigne. He urged the Taiwanese government to resolve the Tai Ji Men case as soon as possible by saying, “We live in a historical moment when Taiwan needs the maximum support from its international friends. But a precondition for its support to be effective is for Taiwan to put its own house in order.”

Willy Fautré, co-founder and director of Human Rights Without Frontiers, also stated that the Tai Ji Men case is not a technical tax dispute, but rather a case of human rights abuses. He said that the bureaucrats who pursued Tai Ji Men were motivated by corruption, including the immoral bonus system for tax collectors and enforcers. To restore human rights, Fautré insisted that these bureaucrats must be prosecuted and punished, and that the sacred land, which was wrongfully confiscated, must be returned to Tai Ji Men.

Tai Ji Men dizi demand that the Taiwanese government implement protection of human rights and freedom, rectify the Tai Ji Men case, return Tai Ji Men’s sacred land, and restore the reputation of Tai Ji Men’s shifu and dizi. Judy Lee, on behalf of worldwide Tai Ji Men dizi, said, “We are going to continue to reach out through the international community to put pressure on the Taiwanese government to correct the mistakes that were made 25 years ago. If it’s not resolved, we will come back!”

Tai Ji Men Qigong Academy: Tai Ji Men is an ancient menpai (similar to school) of qigong, martial arts, and self-cultivation. It has carried forward the wisdom of Taoist philosophy, one of the highest philosophies of humankind. It is an international nonprofit cultural organization. Its contemporary zhang-men-ren (grandmaster), Dr. Hong, Tao-Tze established the Tai Ji Men Qigong Academy in 1966, and since then it has grown to 15 academies worldwide.

Dr. Hong teaches his dizi (similar to disciples) methods to achieve physical, mental, and spiritual balance, and tens of thousands of families have benefited from his teaching. At Tai Ji Men, martial arts and wisdom have been passed down from the shifu (master) to his dizi. Through this time-honored tradition, the shifu and dizi promote the Tai Ji Men culture and martial arts around the world while embodying what is true, good, and beautiful as well as spreading the ideas of conscience, love, and peace. Over the past half-century, the shifu and dizi have self-funded trips to over 300 cities in 101 nations to conduct more than 3,000 cultural performances and exchanges and have been recognized as “International Ambassadors of Peace and Goodwill.”

Media Contact:

Lily Chen
Representative
info@taijimenla.org
626-202-5268
http://www.taijimen.org/TJM2016G_ENG/index.php

A photo accompanying this announcement is available at https://www.globenewswire.com/NewsRoom/AttachmentNg/78d887bf-54bc-4f4c-80f7-8ecea60b1714

Winter Wonderland and Qatar Announce 5-Year Desert Island Deal

Qatar Tourism

Qatar Tourism

DOHA, Qatar, Dec. 13, 2021 (GLOBE NEWSWIRE) — Ground has broken on an exciting new project to bring the world-famous Winter Wonderland to Qatar for five consecutive years, starting November 2022.

Housed on the Al Maha Island near Lusail City just north of Qatar’s capital, Doha Winter Wonderland is a 200,000 square metre venue that will open prior to the FIFA World Cup Qatar 2022™ next November, providing visitors a festive experience during their stay.

Unlike its sister Hyde Park installation in London, which is famous for its variety of festive attractions, activities and entertainment, visitors to Doha Winter Wonderland will find seafront chalets, restaurants, games, and cafes, all under delightful average temperatures in the mid-20°Cs.

Under the patronage and presence of His Excellency Sheikh Khalid bin Khalifa bin Abdulaziz Al Thali, Prime Minister and Minister of Interior, Qatari Diar Company and Qatar Tourism have penned a five-year deal with Elegancia Group to build and operate the project.

Chairman of Qatar Tourism and Qatar Airways Group Chief Executive, His Excellency Mr. Akbar Al Baker, said: “This project, which will be a quality addition to Qatari tourism, is not just a games area, but rather an integrated entertainment destination on par with the foremost entertainment cities in the world.”

Doha Winter Wonderland will include six play areas with more than 50 world-class games for all ages. It will be operated by IMG (International Marketing Group), the same company that manages the event in Hyde Park.

A ground-breaking ceremony on the Al Maha Island was attended by HE Mr. Ali bin Ahmed al-Kuwari, Minister of Finance, HE Sheikh Mohammed bin Hamad bin Qassim al-Thani, Minister of Commerce and Industry, and HE Mr. Jassim bin Saif al-Sulaiti, Minister of Transport. It was also attended by HE Sheikh Khalid bin Khalifa bin Jassim Al Thani, Chairman of the Board of Directors of Qatari Diar, HE Akbar Al Baker, President of Qatar Tourism, HE Eng. Abdullah bin Hamad Al Attiyah, CEO of Qatari Diar, along with many dignitaries.

His Excellency Sheikh Khalid bin Khalifa bin Jassim Al Thani, Chairman of Qatari Diar’s Board of Directors, said: “Once the project is complete, it will not just be a tourist attraction targeting Qatari residents, but one that will go beyond to become a remarkable and distinctive addition to a growing list of world-class tourist destinations in Qatar.”

Eng. Abdullah bin Hamad Al-Attiyah said: “As Lusail City is planned to be a future city that embraces societal diversity, advanced infrastructure, integrated services both public and private, and large local and international institutions and entities, a new world-class entertainment destination such as Doha Winter Wonderland will add a new competitive advantage to the city and will serve as an outlet for residents and visitors.”

Moataz Al Khayat, Chairman of Elegancia Group, said: “We are fortunate to be part of this prestigious project that presents Doha Winter Wonderland as an important milestone in Qatar’s growing and developing tourism sector.”

Further holiday information on Qatar can be found at www.visitqatar.qa.

-Ends-

For media-related inquiries, please contact Qatar Tourism’s Press Office at:

+974 7774 7863 | pressoffice@visitqatar.qa

About Qatar:

Qatar is a peninsula surrounded by the Arabian Gulf in the heart of the Middle East, with 80% of the earth’s population within a six-hour flight. Ranked the safest country in the world in 2020 by Numbeo, Qatar welcomes all travellers, and guests from over 85 countries can enter visa-free. Qatar has an incredible variety of easily accessible tourist attractions, a plethora of fauna and flora including Whale Sharks and the majestic national animal the Arabian Oryx, and most experiences are a unique combination of cultural authenticity and modernity. From iconic museums to high-rise restaurants, from thrilling desert adventures to world-famous events including none other than the FIFA World Cup Qatar 2022™, there is something for all types of travellers and budgets.

About Qatar Tourism:

Qatar Tourism is the official government body responsible for the development and promotion of tourism in Qatar, facilitating the sector’s exponential growth. Qatar is a destination where people of the world come together to experience unique offerings in arts, culture, sports, and adventure, catering to family and business visitors, rooted in Service Excellence. Qatar Tourism seeks to boost the entire tourism value chain, grow local and international visitor demand, attract inward investment, and drive a multiplier effect across the domestic economy. The Qatar Tourism Strategy 2030 sets an ambitious target to attract over six million international visitors a year by 2030, making Qatar the fastest-growing destination in the Middle East.

Web: www.visitqatar.qa

Twitter: @VisitQatar

Instagram: @VisitQatar

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Persons with disabilities jointly present key findings to national counterparts at Platform Event

Organizations of Persons with Disabilities (OPDs) presented the key findings of their recently finalized Joint Submission to the United Nations Committee on the Rights of Persons with Disabilities (CRPD Committee) to the Government, INGOs, United Nations, and other development partners at a Platform Event.

The Lao PDR is one of 184 State-Parties of the UN Convention on the Rights of Persons with Disabilities (CRPD Convention), which commits governments to protect the human rights of persons with disabilities and undertake regular reviews by the CRPD Committee on their progress.

Since ratifying in 2009, the Government of the Lao PDR has made noteworthy achievements in implementing the CRPD Convention, including through the amended 2015 Constitution, Law on Persons with Disabilities, and several other laws and policies on education, healthcare, legal aid, and employment.

In August 2022, the CRPD Committee will review the Lao PDR’s implementation of the CPRD Convention for the first time, together with China, Japan, Bangladesh, Indonesia, and the Republic of Korea.

OPDs play a key role in CRPD Reviews, providing parallel submissions to the CRPD Committee, using data collected by persons with disabilities, and fulfilling the central motto of the CRPD Convention for OPDs: “Nothing about us without us.”

A total of 11 Lao OPDs across 11 provinces contributed to the Joint Submission, representing different disabilities, including persons with sensory impairments, persons with physical difficulties, and those with intellectual disabilities and autism, and their caregivers.

With support from UNDP, the group joined a series of workshops to review national laws, analyze disability data and record the lived experiences of thousands of persons with disabilities on the barriers that continue to exclude them from society.

The UNDP Team Leader for Governance, Mr. Seán O’Connell, remarked, “The OPDs’ Joint Submission to the CRPD Committee signifies the important role OPDs play in ensuring that the unique experiences of persons with disabilities fed into building a more inclusive and sustainable Lao PDR. Today marks a great opportunity for us all to listen to persons with disabilities and understand what is working well and where we can collaborate further to improve their lives.”

At the Platform Event, the OPDs presented their findings, which drew from personal accounts, to draft 78 recommendations to the government across six thematic areas, including law, justice and participation; health; education; work and social protection; rights of women and children with disabilities; and access to public information and infrastructure.

President of the Lao Association for the Deaf, Ms. Phanita Maiphone, said, “the drafting experience has been a great learning opportunity for everyone involved. Not only did each OPD gain a deeper understanding of the Convention, but also of each other and the diverse challenges many persons with disabilities face in the Lao PDR. The process improved our skills in research, teamwork, and advocacy, and we are looking forward to continuing to work together in the CRPD processes.”

International participants commended the government and the OPDs for their positive engagement in their first CRPD Review. The government, OPD, and development partners agreed to work closely together to implement the recommendations made to the Lao PDR under the CRPD in the years ahead.

Source: Lao News Agency

Nonprofits Urge Addition of Deadly Noma Disease to WHO List

The disfiguring disease noma, found mainly in poor areas of sub-Saharan Africa that lack health care, kills 90% of victims, most of them children, when left untreated. Noma is preventable, and to that end, aid groups are urging the World Health Organization to add Noma to its list of neglected tropical diseases.

Eight-year-old Amadou Compaore recently recovered from noma, a little-known tropical disease.

Although noma has scarred his face, Compaore, relatively speaking, is one of the lucky ones. If noma is diagnosed within the first few weeks of infection, it is easily treatable with a course of antibiotics.

His father, Sibiri Compaore, told VOA, he noticed the disease in the run-up to Christmas. To begin with, Amadou said his mouth ached to the point where he couldn’t eat anymore. He even had great difficulty drinking sachets of water.

Compaore senior took his son to the nearest city, Kaya, about 25 kilometers away, where medical staff were able to identify the disease thanks to awareness building by the Swiss non-governmental organization Sentinelles.

Sidi Omar Boena is a nurse at a Sentinelles medical center in Ouagadougou, specializing in the treatment of noma.

He says most health workers in Burkina Faso have not heard of the disease noma and that diagnosing it in people 400 to 500 kilometers from Ouagadougou is very difficult.

He says that he is sometimes forced to diagnose noma with photos sent to him via WhatsApp.

Odette Serene, who also suffered from noma, now receives regular follow-up treatment at the Sentinelles clinic, including support in finding a job.

She now works as a tailor, but she says people still laugh at her, which makes her sad. She says Boena has done a lot to take care of her, however.

Noma is just one of many illnesses currently missing from the World Health Organization’s list of neglected tropical diseases.

Doctors Without Borders, a medical NGO, is running a campaign to have noma added to the WHO list, which already includes diseases like rabies and dengue fever.

“Of course, at the community level, there is discrimination affecting the patients, and so every time there is a case, we might not even be aware because patients are hidden by the communities or they are dying. More than 90% of people are estimated to die,” Jeantet said.

The WHO says when it adds diseases to the list, factors like social stigma and death rates are taken into consideration. The WHO says resources are limited, so some diseases have to be left off.

WHO press officer Ashok Moloo explains the effect of adding a disease to the list.

“It really brings the disease or the condition to another level … It also adds to the advocacy part of the disease, awareness creation and also resources,” Moloo points out.

As for Amadou Compaore, he says what the doctors have done to help him has been an inspiration. He told VOA he wants to become a doctor, to treat people so that they can be cured, like him.

The WHO plans to make possible new additions to its neglected tropical disease list in 2023. It remains to be seen if noma will be among them.

Source: Voice of America